Grants & Publications
Eyes on the Future as part of the global RDH12 Alliance is seeding science all over the world to advance the development of a treatment for those affected by RDH12 Inherited Retinal Dystrophy.
Here a list of the main grants given by the Global RDH12 Alliance (Eyes on the Future, RDH12 Fund for Sight, Candle in the Dark) since 2010:
Grant for pre-clinical work for RDH12 gene therapy (viral/ non viral) – RDH12 Fund for Sight
Grant to explore new models to bring gene therapy for ultrarare to patients – RDH12 Fund for Sight
Grant for pre-clinical work for RDH12 gene therapy – Candle in the Dark
First ever scientific conference on RDH12 with participation from academia, industry, patients, charities, regulators.
3 years grant then extended to a 4th year to develop in vitro and animal RDH12 disease models, study the RDH12 disease mechanism and test potential compounds to slow down the sight progression – Eyes on the Future/ Through Vicky’s Eyes in partnership with Retina UK and Moorfields Eye Charity
Support to the UPenn RDH12 Natural History Study – RDH12 Fund for Sight
2 editions of the global RDH12 landscape study – Eyes on the Future/ Through Vicky’s Eyes
Grant for pre-clinical RDH12 gene therapy including mouse model – RDH12 Fund for Sight
Early seed grant – Candle in the Dark
Early seed grant for pre-clinical RDH12 gene therapy – RDH12 Fund for Sight
Key RDH12 Publications
Generation of Two Human iPSC Lines, H.Sarkar et al– July 2021
RDH12 Scientific Landscape, F.Sofia et al – 2021
RDH12 Scientific Workshop, F.Sofia et al– 2020
Novel Heterozygous Deletion in Retinol Dehydrogenase 12, M.Moosajee et al – 2020
Development of a Gene Therapy RDH12,Debra A. Thompson et al- 2019
Retinol Dehydrogenase 12 (RDH12): Role in Vision, Retinal Disease and Future Perspectives, M.Moosajee et al– 2019
Phenotypic Variability Of Recessive RDH12- Xuan Zou et al -2019
Detailed Clinical Characterisation, Unique Features and Natural History of Autosomal Recessive – Abigail T Fahim et al – 2019
RDH12 Mutations Cause a Severe Retinal Degeneration With Relatively Spared Rod Function– Tomas S Aleman et al- 2018